Published on Fri Sep 17 2021

Long-term Outcomes after Postnatal Cytomegalovirus Infection in Low Birthweight Preterm Infants: A Systematic Review.

Ashley Stark, Sarah Cantrell, Rachel G Greenberg, Sallie R Permar, Kristin E D Weimer

Cytomegalovirus is the most common viral infection seen in newborns. Postnatally acquired CMV (pCMV) infection rarely results in serious manifestations in term infants. Long-term implications of pCMV infection of preterm infants are unknown.

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Abstract

Cytomegalovirus (CMV) is the most common viral infection seen in newborns. Although postnatally acquired CMV (pCMV) infection rarely results in serious manifestations in term infants, preterm infants can develop severe clinical illness. However, the long-term implications of pCMV infection of preterm infants are unknown. Few robust studies on long-term outcomes of pCMV infection have been performed, and those reported often present conflicting results. Our objective was to assess the long-term outcomes for low birthweight (LBW) preterm infants after pCMV infection.