Published on Sun Jan 10 2021

Coronaviruses and SARS-CoV-2: A Brief Overview.

Stephan Ludwig, Alexander Zarbock

In late December 2019, several cases of pneumonia of unknown origin were reported from China. In early January 2020, these cases were announced to be caused by a novel coronavirus. The virus was later denominated severe acute respiratory syndrome coronav virus 2 (SARS-CoV-2)

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Abstract

In late December 2019, several cases of pneumonia of unknown origin were reported from China, which in early January 2020 were announced to be caused by a novel coronavirus. The virus was later denominated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and defined as the causal agent of coronavirus disease 2019 (COVID-19). Despite massive attempts to contain the disease in China, the virus has spread globally, and COVID-19 was declared a pandemic by the World Health Organization (WHO) in March 2020. Here we provide a short background on coronaviruses, and describe in more detail the novel SARS-CoV-2 and attempts to identify effective therapies against COVID-19.