Published on Sun Aug 01 2021

Transarterial Chemoembolization in Patients with Hepatocellular Carcinoma with Intra-atrial Tumor Extension: Imaging Response and Oncologic Outcomes.

Andrew Kolarich, Constantine Frangakis, Mark Yarchoan, Kelvin Hong, Christos Georgiades

Transarterial chemoembolization alone or in combination with systemic therapy yields an improved imaging response and may be associated with improved survival. The study looked at patients with right atrial (RA) hepatocellular carcinoma extension treated with transarterial chemotherapy.

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Abstract

To evaluate outcomes in patients with right atrial (RA) hepatocellular carcinoma extension treated with transarterial chemoembolization. Eight patients were retrospectively reviewed. Follow-up visits occurred at 4-6 weeks; transarterial chemoembolization was repeated if residual tumor persisted. After transarterial chemoembolization, RA tumor volume reduction was 86% ± 19; α-fetoprotein level showed a reduction of 95%. From RA tumor diagnosis, 3-, 6-, and 12-month overall survival was 100% ± 0, 100% ± 0, and 67% ± 29, respectively. In patients with hepatocellular carcinoma invading the right atrium, transarterial chemoembolization alone or in combination with systemic therapy yields an improved imaging response and may be associated with improved survival.