Published on Tue Nov 13 2018

Association of season of birth with DNA methylation and allergic disease.

G A Lockett, N Soto-Ramírez, M A Ray, T M Everson, C-J Xu, V K Patil, W Terry, A Kaushal, F I Rezwan, S L Ewart, U Gehring, D S Postma, G H Koppelman, S H Arshad, H Zhang, W Karmaus, J W Holloway

The environment affects DNA methylation, with potentially long-lasting effects on gene expression and disease. Season of birth influences allergy risk; however, the biological mechanisms underlying this observation are unclear.

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Abstract

Season of birth influences allergy risk; however, the biological mechanisms underlying this observation are unclear. The environment affects DNA methylation, with potentially long-lasting effects on gene expression and disease. This study examined whether DNA methylation could underlie the association between season of birth and allergy.