Published on Wed Aug 11 2021

Renal Outcomes After Simultaneous Liver-Kidney Transplantation: Results from the US Multicenter Simultaneous Liver-Kidney Transplantation Consortium.

Pratima Sharma, Zhiyu Sui, Min Zhang, John C Magee, Pranab Barman, Yuval Patel, Aaron Schluger, Kara Walter, Scott W Biggins, Giuseppe Cullaro, Randi Wong, Jennifer C Lai, Jennifer Jo, Jasmine Sinha, Lisa VanWagner, Elizabeth C Verna
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Abstract

Simultaneous liver-kidney transplantation (SLKT) is increasingly common in the United States. However, little is known about the renal-related outcomes following SLKT, which are essential to maximize the health of these allografts. We examined the factors impacting renal function following SLKT. This is an observational multicenter cohort study from the US Multicenter SLKT Consortium consisting of recipients of SLKT aged ≥18 years of transplantations performed between February 2002 and June 2017 at 6 large US centers in 6 different United Network for Organ Sharing regions. The primary outcome was incident post-SLKT stage 4-5 chronic kidney disease (CKD) defined as <30 mL/minute/1.73 m